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Hypertension and Heart Failure - Epidemiology,  Mechanisms and Treatment (Hardcover, 1st ed. 2019): Maria Dorobantu, Giuseppe... Hypertension and Heart Failure - Epidemiology, Mechanisms and Treatment (Hardcover, 1st ed. 2019)
Maria Dorobantu, Giuseppe Mancia, Guido Grassi, Victor Voicu
R3,204 R2,575 Discovery Miles 25 750 Save R629 (20%) Ships in 12 - 17 working days

This book explains how hypertension affects 20-50% of the adult population in developed countries. Heart failure is the result of the hypertension's effects on the heart and it represents a growing public health problem. In this context the international scientific community is continuously struggling to develop better strategies in screening, diagnosing and treating hypertension and its deleterious effects. Thus, this field is continuously changing, with new important information being added constantly. This volume will offer both insights into the intimate mechanisms of transition from hypertension to heart failure and clinical practice advice on the prevention and treatment of heart failure in hypertensive population. The mechanisms which explain the progression from hypertension to heart failure will be also covered exhaustively by offering two chapters referring to the diagnosis of heart failure in hypertensive population and one regarding echocardiography which is the most frequently used imaging method in clinical practice. The reader will be also provided with information on cardiovascular magnetic resonance which has the unique advantage of differentiating hypertensive heart failure from other pathologies associated with increased myocardial thickness. This book is a useful tool for clinicians but also to the research community interested in heart failure and consequences of hypertension on heart who want to be up-to-date with the new developments in the field.

Manual of Hypertension of the European Society of Hypertension, Third Edition (Hardcover, 3rd New edition): Giuseppe Mancia,... Manual of Hypertension of the European Society of Hypertension, Third Edition (Hardcover, 3rd New edition)
Giuseppe Mancia, Guido Grassi, Anna Dominiczak, Konstantinos Tsioufis, Enrico Agabiti Rosei
R3,839 Discovery Miles 38 390 Ships in 12 - 17 working days

The Manual of Hypertension of the European Society of Hypertension reflects emerging concepts that have the potential to impact diagnostic and therapeutic approaches to hypertension. Updating all material, this new edition also delves into a number of areas that have received heightened interest in recent years or have become a matter of debate due to the controversial interpretation of the available data. Reflects emerging concepts impacting diagnostic and therapeutic approaches Explores background, history, epidemiology, and risk factors Describes pharmacological, nonpharmacological, and medical treatments Examines hypertension in special populations and treatment

Prehypertension and Cardiometabolic Syndrome (Hardcover, 1st ed. 2019): Reuven Zimlichman, Stevo Julius, Giuseppe Mancia Prehypertension and Cardiometabolic Syndrome (Hardcover, 1st ed. 2019)
Reuven Zimlichman, Stevo Julius, Giuseppe Mancia
R5,269 R3,993 Discovery Miles 39 930 Save R1,276 (24%) Ships in 12 - 17 working days

This book sheds new light on the management of patients with borderline cardiovascular risk factors in order to prevent their progression to end organ damage. The book stimulates discussion of this poorly understood condition and lays the groundwork for developing recommendations and guidelines. While the diagnostic and therapeutic approach to full-blown diabetes, hypertension, dyslipidemia and obesity is well defined, there is still a lack of clear understanding and guidelines as far as patients with borderline conditions - especially when multiple - are concerned. Moreover, end-organ damage depends on several factors, including genetic factors, making it difficult to predict its extent. As such, the gradual transition from a healthy subject to one with functional hemodynamic changes, and then one with structurally asymptomatic changes and lastly to overt disease needs further investigation. In order to address these knowledge gaps, the book covers a broad variety of topics, making it a valuable tool for identifying which asymptomatic subjects could profit from being appropriately screened and at what stage. Furthermore it offers insights into better treating these patients to prevent their progression to overt disease. The book appeals to cardiologists, primary care physicians and all those healthcare professional looking to optimize the management of these complex and often undiagnosed cases.

Assessment of Preclinical Organ Damage in Hypertension (Hardcover, 2015 ed.): Enrico Agabiti Rosei, Giuseppe Mancia Assessment of Preclinical Organ Damage in Hypertension (Hardcover, 2015 ed.)
Enrico Agabiti Rosei, Giuseppe Mancia
R2,989 R2,368 Discovery Miles 23 680 Save R621 (21%) Ships in 12 - 17 working days

This book presents up-to-date information on how to assess early preclinical alterations in the heart, the small and large arteries and the kidney using the most sensitive, specific and cost-effective techniques. A wide variety of techniques are discussed, with careful attention to the latest developments. For each organ, evidence is documented regarding the prevalence of organ damage in the general and the hypertensive population. Information is provided on the potential induction of regression of organ damage by treatment, the criteria for establishing significant changes and the clinical prognostic significance of regression. The manual will be invaluable for all practitioners responsible for the clinical management of hypertensive patients, given that the assessment of early preclinical cardiovascular and renal damage permits more accurate risk stratification at baseline and facilitates evaluation of cardiovascular protection when regression of structural changes is achieved during treatment.

Cardiorenal Syndrome - Mechanisms, Risk and Treatment (Hardcover, 2010 ed.): Adel E. Berbari, Giuseppe Mancia Cardiorenal Syndrome - Mechanisms, Risk and Treatment (Hardcover, 2010 ed.)
Adel E. Berbari, Giuseppe Mancia
R3,916 R3,138 Discovery Miles 31 380 Save R778 (20%) Ships in 12 - 17 working days

Chronic kidney disease with a worldwide prevalence of 10% in the general population is emerging as a major public health priority. Renal dysfunction is associated with a high risk for cardiovascular complications. The relationship between renal insufficiency and cardiovascular disease, termed the cardiorenal syndrome exists whether impairment of renal function is a consequence of primary renal parenchymal disease or primary heart disease.

Several pathophysiologic mechanisms have been postulated to explain the relationship between renal dysfunction and cardiovascular disease. Recent studies indicate an integrated response of the vascular smooth muscles and glomerular mesangial cells to traditional and uremia related cardiovascular risk factors. Traditional risk factors can incite renal impairment and cardiac damage. As renal function deteriorates, uremia-related risk factors play an increasing role both in reduction in glomerular filtration rate and cardiovascular damage. Several uremia related factors such as uncontrolled hypertension, disturbed glucose insulin metabolism, microalbuminuria, phosphate retention, secondary hyperparathyroidism, myocardial and vascular calcification, hypertensive-uremic cardiomyopathy, inflammation, oxidant injury, and neurohormonal dysregulation have been implicated in the pathogenesis of the cardiorenal syndrome. Recent data suggest that management of the cardiorenal syndrome requires aggressive control of traditional risk factors as well novel approaches to prevent or reverse uremia related processes.

This book provides a comprehensive update analysis of our current understanding of the cardiorenal syndrome including epidemiology, pathophysiologic mechanisms, and therapeutic approaches.

White Coat Hypertension - An Unresolved Diagnostic and Therapeutic Problem (Hardcover, 2015 ed.): Giuseppe Mancia, Guido... White Coat Hypertension - An Unresolved Diagnostic and Therapeutic Problem (Hardcover, 2015 ed.)
Giuseppe Mancia, Guido Grassi, Gianfranco Parati, Alberto Zanchetti
R2,298 Discovery Miles 22 980 Ships in 12 - 17 working days

This book addresses all aspects of white coat hypertension the phenomenon of raised blood pressure in a medical setting yet not elsewhere from its history to its pathophysiology, diagnosis and treatment. White coat hypertension is a common condition, accounting for 30 40% of the overall hypertensive population. While many studies have addressed this condition, controversy still exists over whether it causes an increased risk to sufferers and should be treated.

In the volume neurogenic and non-neurogenic mechanisms are discussed and the significance of various predictive factors, evaluated. The association of white coat hypertension with dysmetabolic risk factors, new-onset diabetes and other conditions is carefully reviewed. Further chapters consider the occurrence of asymptomatic organ damage and cardiovascular outcomes in affected patients and helpful guidance is also provided on the controversial issue of when to treat and when not to treat. "White Coat Hypertension" is based largely on work done during the past 30 years by renowned researchers working in Milan, who have made key contributions in improving knowledge of the condition and whose work is well known across the world."

Disorders of Blood Pressure Regulation - Phenotypes, Mechanisms, Therapeutic Options (Hardcover, 1st ed. 2018): Adel E.... Disorders of Blood Pressure Regulation - Phenotypes, Mechanisms, Therapeutic Options (Hardcover, 1st ed. 2018)
Adel E. Berbari, Giuseppe Mancia
R6,380 R5,236 Discovery Miles 52 360 Save R1,144 (18%) Ships in 12 - 17 working days

This book aims to present a comprehensive classification of hypertensive phenotypes based on underlying target organ involvement. Particular emphasis is placed on review and assessment of clinical presentation, pathophysiologic mechanisms, and possible specific therapeutic options for each hypertension phenotype. Several of these phenotypes are well known and well described in the literature, such as prehypertension, white coat and masked hypertension, isolated systolic hypertension, renovascular hypertension, endocrine hypertension, pediatric hypertension, and gestational hypertension. Other hypertension phenotypes, however, are not widely recognized, being reported only in special reviews; examples include hypertension associated with renal calculus disease and other rarer causes such as Turner syndrome, herbal and medicinal compounds, and pharmacologic agents. A detailed account of the various causes of monogenic hypertension is also included. Finally, a section is devoted to general aspects of hypertension, including the significance of blood pressure indices, the natural course of untreated and treated hypertension, hypertension mechanisms, genetics, and guidelines for blood pressure control.

New Concepts in Stroke Diagnosis and Therapy, (Current Developments in Stroke, Volume 1) (Paperback): Giuseppe Mancia, Carlo... New Concepts in Stroke Diagnosis and Therapy, (Current Developments in Stroke, Volume 1) (Paperback)
Giuseppe Mancia, Carlo Ferrarese, Simone Beretta
R2,184 R2,014 Discovery Miles 20 140 Save R170 (8%) Ships in 7 - 11 working days
Special Issues in Hypertension (Paperback, 2012 ed.): Adel E. Berbari, Giuseppe Mancia Special Issues in Hypertension (Paperback, 2012 ed.)
Adel E. Berbari, Giuseppe Mancia
R4,605 Discovery Miles 46 050 Ships in 7 - 11 working days

This book is not intended as a full detailed report on hypertension and related disorders, but instead focuses on particular issues in hypertension. It looks at emerging recently described forms of hypertension that are frequently encountered in clinical practice (prehypertension, white-coat and masked hypertension, hypertension in the elderly) and discusses novel aspects of target organ disease (for example, cognitive impairment, dementia, and sexual dysfunction), and changing concepts in the management of hypertension and antihypertensive pharmacotherapy. It also looks at specific topics that are rarely discussed in books, including hypertension control in postmenopausal women on hormonal replacement therapy, Ramadan fasting, painful inflammatory disorders, and aldosterone escape. Finally, it examines newer cardiovascular risk factors (for example, uric acid, circadian blood pressure changes, blood pressure variability).

Cardiorenal Syndrome - Mechanisms, Risk and Treatment (Paperback, 2010 ed.): Adel E. Berbari, Giuseppe Mancia Cardiorenal Syndrome - Mechanisms, Risk and Treatment (Paperback, 2010 ed.)
Adel E. Berbari, Giuseppe Mancia
R3,860 Discovery Miles 38 600 Ships in 7 - 11 working days

Chronic kidney disease with a worldwide prevalence of 10% in the general population is emerging as a major public health priority. Renal dysfunction is associated with a high risk for cardiovascular complications. The relationship between renal insufficiency and cardiovascular disease, termed the cardiorenal syndrome exists whether impairment of renal function is a consequence of primary renal parenchymal disease or primary heart disease. Several pathophysiologic mechanisms have been postulated to explain the relationship between renal dysfunction and cardiovascular disease. Recent studies indicate an integrated response of the vascular smooth muscles and glomerular mesangial cells to traditional and uremia related cardiovascular risk factors. Traditional risk factors can incite renal impairment and cardiac damage. As renal function deteriorates, uremia-related risk factors play an increasing role both in reduction in glomerular filtration rate and cardiovascular damage. Several uremia related factors such as uncontrolled hypertension, disturbed glucose insulin metabolism, microalbuminuria, phosphate retention, secondary hyperparathyroidism, myocardial and vascular calcification, hypertensive-uremic cardiomyopathy, inflammation, oxidant injury, and neurohormonal dysregulation have been implicated in the pathogenesis of the cardiorenal syndrome. Recent data suggest that management of the cardiorenal syndrome requires aggressive control of traditional risk factors as well novel approaches to prevent or reverse uremia -related processes. This book provides a comprehensive update analysis of our current understanding of the cardiorenal syndrome including epidemiology, pathophysiologic mechanisms, and therapeutic approaches.

Special Issues in Hypertension (Hardcover, 2012 ed.): Adel E. Berbari, Giuseppe Mancia Special Issues in Hypertension (Hardcover, 2012 ed.)
Adel E. Berbari, Giuseppe Mancia
R4,274 Discovery Miles 42 740 Ships in 7 - 11 working days

This book is not intended as a full detailed report on hypertension and related disorders, but instead focuses on particular issues in hypertension. It looks at emerging recently described forms of hypertension that are frequently encountered in clinical practice (prehypertension, white-coat and masked hypertension, hypertension in the elderly) and discusses novel aspects of target organ disease (for example, cognitive impairment, dementia, and sexual dysfunction), and changing concepts in the management of hypertension and antihypertensive pharmacotherapy. It also looks at specific topics that are rarely discussed in books, including hypertension control in postmenopausal women on hormonal replacement therapy, Ramadan fasting, painful inflammatory disorders, and aldosterone escape. Finally, it examines newer cardiovascular risk factors (for example, uric acid, circadian blood pressure changes, blood pressure variability).

Resistant Hypertension - Epidemiology, Pathophysiology, Diagnosis and Treatment (Hardcover, 2013 ed.): Giuseppe Mancia Resistant Hypertension - Epidemiology, Pathophysiology, Diagnosis and Treatment (Hardcover, 2013 ed.)
Giuseppe Mancia
R3,663 R2,938 Discovery Miles 29 380 Save R725 (20%) Ships in 12 - 17 working days

A growing number of people suffer from so-called resistant hypertension, that is to say, high blood pressure that does not respond to treatment. This disorder is of great current interest and importance for public health, being a common clinical problem faced by both primary care clinicians and specialists. Furthermore, as older age and obesity are among the strongest risk factors for uncontrolled hypertension, the incidence of resistant hypertension will likely increase as the population becomes more elderly and heavier. While the prognosis of resistant hypertension is unknown, cardiovascular risk is undoubtedly increased since patients often have a history of long-standing, severe hypertension complicated by multiple other cardiovascular risk factors. This volume, compiled by a panel of world-renowned experts, offers a comprehensive exploration of resistant hypertension, covering epidemiology, complex diagnostic aspects, and the therapeutic options currently available, with due attention to overall treatment strategies. New therapeutic agents and procedures, such as renal denervation and baroreceptor stimulation, are also described. In addition, the book addresses the economic aspects of resistant hypertension and the role of the different professional figures, from GPs to hypertension specialists, in dealing with it.

Arterial Disorders - Definition, Clinical Manifestations, Mechanisms and Therapeutic Approaches (Hardcover, 2015 ed.): Adel... Arterial Disorders - Definition, Clinical Manifestations, Mechanisms and Therapeutic Approaches (Hardcover, 2015 ed.)
Adel Berbari, Giuseppe Mancia
R3,500 R2,817 Discovery Miles 28 170 Save R683 (20%) Ships in 12 - 17 working days

As our knowledge about arterial disease is greatly expanding, the aim of this book is to explore all aspects of arterial pathology, including classification, clinical manifestations, pathogenesis, and therapeutic options. The discussion of pathophysiologic mechanisms of arterial disease is wide ranging, encompassing hemodynamic, metabolic, humoral, inflammatory, genetic and environmental factors. Particular emphasis is placed on recent concepts, such as: the role of age-associated arterial alterations in the initiation and progression of cardiovascular diseases in older persons, the importance of mineral metabolism-bone vascular interactions, the clinical and prognostic significance of the renal resistive index, retinal circulation, toxemia of pregnancy as an arterial disease, and the role of pulmonary/vascular interaction in pulmonary hypertension and cross-talk of macrocirculation and microcirculation in target organ involvement. Evaluation procedures are carefully explained, and the full range of currently available therapeutic options, including lifestyle modifications and pharmacologic approaches, are described and appraised.

White Coat Hypertension - An Unresolved Diagnostic and Therapeutic Problem (Paperback, Softcover reprint of the original 1st... White Coat Hypertension - An Unresolved Diagnostic and Therapeutic Problem (Paperback, Softcover reprint of the original 1st ed. 2015)
Giuseppe Mancia, Guido Grassi, Gianfranco Parati, Alberto Zanchetti
R2,002 Discovery Miles 20 020 Ships in 7 - 11 working days

This book addresses all aspects of white coat hypertension - the phenomenon of raised blood pressure in a medical setting yet not elsewhere - from its history to its pathophysiology, diagnosis and treatment. White coat hypertension is a common condition, accounting for 30-40% of the overall hypertensive population. While many studies have addressed this condition, controversy still exists over whether it causes an increased risk to sufferers and should be treated. In the volume neurogenic and non-neurogenic mechanisms are discussed and the significance of various predictive factors, evaluated. The association of white coat hypertension with dysmetabolic risk factors, new-onset diabetes and other conditions is carefully reviewed. Further chapters consider the occurrence of asymptomatic organ damage and cardiovascular outcomes in affected patients and helpful guidance is also provided on the controversial issue of when to treat and when not to treat. White Coat Hypertension is based largely on work done during the past 30 years by renowned researchers working in Milan, who have made key contributions in improving knowledge of the condition and whose work is well known across the world.

Arterial Disorders - Definition, Clinical Manifestations, Mechanisms and Therapeutic Approaches (Paperback, Softcover reprint... Arterial Disorders - Definition, Clinical Manifestations, Mechanisms and Therapeutic Approaches (Paperback, Softcover reprint of the original 1st ed. 2015)
Adel Berbari, Giuseppe Mancia
R2,952 Discovery Miles 29 520 Out of stock

As our knowledge about arterial disease is greatly expanding, the aim of this book is to explore all aspects of arterial pathology, including classification, clinical manifestations, pathogenesis, and therapeutic options. The discussion of pathophysiologic mechanisms of arterial disease is wide ranging, encompassing hemodynamic, metabolic, humoral, inflammatory, genetic and environmental factors. Particular emphasis is placed on recent concepts, such as: the role of age-associated arterial alterations in the initiation and progression of cardiovascular diseases in older persons, the importance of mineral metabolism-bone vascular interactions, the clinical and prognostic significance of the renal resistive index, retinal circulation, toxemia of pregnancy as an arterial disease, and the role of pulmonary/vascular interaction in pulmonary hypertension and cross-talk of macrocirculation and microcirculation in target organ involvement. Evaluation procedures are carefully explained, and the full range of currently available therapeutic options, including lifestyle modifications and pharmacologic approaches, are described and appraised.

Home Blood Pressure Monitoring (Hardcover, 1st ed. 2020): George S. Stergiou, Gianfranco Parati, Giuseppe Mancia Home Blood Pressure Monitoring (Hardcover, 1st ed. 2020)
George S. Stergiou, Gianfranco Parati, Giuseppe Mancia
R1,977 Discovery Miles 19 770 Out of stock

Hypertension remains a leading cause of disability and death worldwide. Self-monitoring of blood pressure by patients at home is currently recommended as a valuable tool for the diagnosis and management of hypertension. Unfortunately, in clinical practice, home blood pressure monitoring is often inadequately implemented, mostly due to the use of inaccurate devices and inappropriate methodologies. Thus, the potential of the method to improve the management of hypertension and cardiovascular disease prevention has not yet been exhausted. This volume presents the available evidence on home blood pressure monitoring, discusses its strengths and limitations, and presents strategies for its optimal implementation in clinical practice. Written by distinguished international experts, it offers a complete source of information and guide for practitioners and researchers dealing with the management of hypertension.

Assessment of Preclinical Organ Damage in Hypertension (Paperback, Softcover reprint of the original 1st ed. 2015): Enrico... Assessment of Preclinical Organ Damage in Hypertension (Paperback, Softcover reprint of the original 1st ed. 2015)
Enrico Agabiti Rosei, Giuseppe Mancia
R2,677 Discovery Miles 26 770 Out of stock

This book presents up-to-date information on how to assess early preclinical alterations in the heart, the small and large arteries and the kidney using the most sensitive, specific and cost-effective techniques. A wide variety of techniques are discussed, with careful attention to the latest developments. For each organ, evidence is documented regarding the prevalence of organ damage in the general and the hypertensive population. Information is provided on the potential induction of regression of organ damage by treatment, the criteria for establishing significant changes and the clinical prognostic significance of regression. The manual will be invaluable for all practitioners responsible for the clinical management of hypertensive patients, given that the assessment of early preclinical cardiovascular and renal damage permits more accurate risk stratification at baseline and facilitates evaluation of cardiovascular protection when regression of structural changes is achieved during treatment.

Home Blood Pressure Monitoring (Paperback, 1st ed. 2020): George S. Stergiou, Gianfranco Parati, Giuseppe Mancia Home Blood Pressure Monitoring (Paperback, 1st ed. 2020)
George S. Stergiou, Gianfranco Parati, Giuseppe Mancia
R1,487 Discovery Miles 14 870 Out of stock

Hypertension remains a leading cause of disability and death worldwide. Self-monitoring of blood pressure by patients at home is currently recommended as a valuable tool for the diagnosis and management of hypertension. Unfortunately, in clinical practice, home blood pressure monitoring is often inadequately implemented, mostly due to the use of inaccurate devices and inappropriate methodologies. Thus, the potential of the method to improve the management of hypertension and cardiovascular disease prevention has not yet been exhausted. This volume presents the available evidence on home blood pressure monitoring, discusses its strengths and limitations, and presents strategies for its optimal implementation in clinical practice. Written by distinguished international experts, it offers a complete source of information and guide for practitioners and researchers dealing with the management of hypertension.

Interventional Therapies for Secondary and Essential Hypertension (Paperback, Softcover reprint of the original 1st ed. 2016):... Interventional Therapies for Secondary and Essential Hypertension (Paperback, Softcover reprint of the original 1st ed. 2016)
Costas Tsioufis, Roland E Schmieder, Giuseppe Mancia
R2,950 Discovery Miles 29 500 Out of stock

This book aims to describe the role of interventional therapies in various forms of secondary hypertension and to explain the ability of such approaches to address unmet needs in the setting of uncontrolled essential hypertension. The coverage encompasses interventions in the full range of relevant conditions, including the various specific pathologies responsible for secondary hypertension, such as renal artery stenosis, coarctation of the aorta, and adrenal tumors. In each case, up-to-date information is presented on indications, procedural aspects, and patient follow-up. A further focus is the most recent knowledge on the use of invasive neuromodulation, such as renal sympathetic denervation and baroreflex stimulation. The text is supplemented by helpful explanatory diagrams and treatment algorithms. A comprehensive clinical guide of this nature has to date been absent from the literature. The book will be of interest to clinicians managing hypertensive patients, researchers investigating advanced hypertension management, and students on cardiovascular courses.

Disorders of Blood Pressure Regulation - Phenotypes, Mechanisms, Therapeutic Options (Paperback, Softcover reprint of the... Disorders of Blood Pressure Regulation - Phenotypes, Mechanisms, Therapeutic Options (Paperback, Softcover reprint of the original 1st ed. 2018)
Adel E. Berbari, Giuseppe Mancia
R6,462 Discovery Miles 64 620 Out of stock

This book aims to present a comprehensive classification of hypertensive phenotypes based on underlying target organ involvement. Particular emphasis is placed on review and assessment of clinical presentation, pathophysiologic mechanisms, and possible specific therapeutic options for each hypertension phenotype. Several of these phenotypes are well known and well described in the literature, such as prehypertension, white coat and masked hypertension, isolated systolic hypertension, renovascular hypertension, endocrine hypertension, pediatric hypertension, and gestational hypertension. Other hypertension phenotypes, however, are not widely recognized, being reported only in special reviews; examples include hypertension associated with renal calculus disease and other rarer causes such as Turner syndrome, herbal and medicinal compounds, and pharmacologic agents. A detailed account of the various causes of monogenic hypertension is also included. Finally, a section is devoted to general aspects of hypertension, including the significance of blood pressure indices, the natural course of untreated and treated hypertension, hypertension mechanisms, genetics, and guidelines for blood pressure control.

Resistant Hypertension - Epidemiology, Pathophysiology, Diagnosis and Treatment (Paperback, Softcover reprint of the original... Resistant Hypertension - Epidemiology, Pathophysiology, Diagnosis and Treatment (Paperback, Softcover reprint of the original 1st ed. 2013)
Giuseppe Mancia
R3,024 Discovery Miles 30 240 Out of stock

A growing number of people suffer from so-called resistant hypertension, that is to say, high blood pressure that does not respond to treatment. This disorder is of great current interest and importance for public health, being a common clinical problem faced by both primary care clinicians and specialists. Furthermore, as older age and obesity are among the strongest risk factors for uncontrolled hypertension, the incidence of resistant hypertension will likely increase as the population becomes more elderly and heavier. While the prognosis of resistant hypertension is unknown, cardiovascular risk is undoubtedly increased since patients often have a history of long-standing, severe hypertension complicated by multiple other cardiovascular risk factors. This volume, compiled by a panel of world-renowned experts, offers a comprehensive exploration of resistant hypertension, covering epidemiology, complex diagnostic aspects, and the therapeutic options currently available, with due attention to overall treatment strategies. New therapeutic agents and procedures, such as renal denervation and baroreceptor stimulation, are also described. In addition, the book addresses the economic aspects of resistant hypertension and the role of the different professional figures, from GPs to hypertension specialists, in dealing with it.

Interventional Therapies for Secondary and Essential Hypertension (Hardcover, 1st ed. 2016): Costas Tsioufis, Roland E... Interventional Therapies for Secondary and Essential Hypertension (Hardcover, 1st ed. 2016)
Costas Tsioufis, Roland E Schmieder, Giuseppe Mancia
R3,892 Discovery Miles 38 920 Out of stock

This book aims to describe the role of interventional therapies in various forms of secondary hypertension and to explain the ability of such approaches to address unmet needs in the setting of uncontrolled essential hypertension. The coverage encompasses interventions in the full range of relevant conditions, including the various specific pathologies responsible for secondary hypertension, such as renal artery stenosis, coarctation of the aorta, and adrenal tumors. In each case, up-to-date information is presented on indications, procedural aspects, and patient follow-up. A further focus is the most recent knowledge on the use of invasive neuromodulation, such as renal sympathetic denervation and baroreflex stimulation. The text is supplemented by helpful explanatory diagrams and treatment algorithms. A comprehensive clinical guide of this nature has to date been absent from the literature. The book will be of interest to clinicians managing hypertensive patients, researchers investigating advanced hypertension management, and students on cardiovascular courses.

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