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Showing 1 - 2 of 2 matches in All departments

Medicinal Chemistry Approaches to Personalized Medicine (Hardcover): Karen Lackey, Bruce Roth Medicinal Chemistry Approaches to Personalized Medicine (Hardcover)
Karen Lackey, Bruce Roth; Series edited by Raimund Mannhold, Hugo Kubinyi, Gerd Folkers
R3,343 R2,346 Discovery Miles 23 460 Save R997 (30%) Shipped within 7 - 13 working days

Edited by two renowned medicinal chemists who have pioneered the development of personalized therapies in their respective fields, this authoritative analysis of what is already possible is the first of its kind, and the only one to focus on drug development issues. Numerous case studies from the first generation of "personalized drugs" are presented, highlighting the challenges and opportunities for pharmaceutical development. While the majority of these examples are taken from the field of cancer treatment, other key emerging areas, such as neurosciences and inflammation, are also covered. With its careful balance of current and future approaches, this handbook is a prime knowledge source for every drug developer, and one that will remain up to date for some time to come. From the content: * Discovery of Predictive Biomarkers for Anticancer Drugs * Discovery and Development of Vemurafenib * Targeting Basal-Cell Carcinoma * G-Quadruplexes as Therapeutic Targets in Cancer * From Human Genetics to Drug Candidates: An Industrial Perspective on LRRK2 Inhibition as a Treatment for Parkinson's Disease * Therapeutic Potential of Kinases in Asthma * DNA Damage Repair Pathways and Synthetic Lethality * Medicinal Chemistry in the Context of the Human Genome and many more

Gene Family Targeted Molecular Design (Hardcover, New): Karen Lackey Gene Family Targeted Molecular Design (Hardcover, New)
Karen Lackey
R2,384 R1,679 Discovery Miles 16 790 Save R705 (30%) Shipped within 7 - 13 working days

As research progresses and information continues to proliferate in the field of molecular design for therapeutic use, there is a need for a reference that brings current theory and proven practice together in a how-to volume. This reference guides scientists new to the field on how to design small molecules that interact with critical protein targets. The chapters condense useful material into a manageable format which is carefully organized and presented. It offers an essential resource for a variety of chemists in academia, and the biotech and pharmaceutical industries, as well as professionals in complementary fields.

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