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Vaccines and Autoimmunity (Hardcover): Yehuda Shoenfeld, Nancy Agmon Levin, Lucija Tomljenovic Vaccines and Autoimmunity (Hardcover)
Yehuda Shoenfeld, Nancy Agmon Levin, Lucija Tomljenovic
R4,330 R3,041 Discovery Miles 30 410 Save R1,289 (30%) Ships in 7 - 13 working days

In light of the discovery of Autoimmune Syndrome Induced by Adjuvants, or ASIA, Vaccines and Autoimmunity explores the role of adjuvants specifically aluminum in different vaccines and how they can induce diverse autoimmune clinical manifestations in genetically prone individuals. Vaccines and Autoimmunity is divided into three sections; the first contextualizes the role of adjuvants in the framework of autoimmunity, covering the mechanism of action of adjuvants, experimental models of adjuvant induced autoimmune diseases, infections as adjuvants, the Gulf War Syndrome, sick-building syndrome (SBS), safe vaccines, toll-like receptors, TLRS in vaccines, pesticides as adjuvants, oil as adjuvant, mercury, aluminum and autoimmunity. The following section reviews literature on vaccines that have induced autoimmune conditions such as MMR and HBV, among others. The final section covers diseases in which vaccines were known to be the solicitor for instance, systemic lupus erythematosus and whether it can be induced by vaccines for MMR, HBV, HCV, and others. Edited by leaders in the field, Vaccines and Autoimmunity is an invaluable resource for advanced students and researchers working in pathogenic and epidemiological studies.

Autoimmunity, Part D - Autoimmune Disease, Annus Mirabilis, Volume 1108 (Paperback): Yehuda Shoenfeld, M.E. Gershwin Autoimmunity, Part D - Autoimmune Disease, Annus Mirabilis, Volume 1108 (Paperback)
Yehuda Shoenfeld, M.E. Gershwin
R3,569 R2,518 Discovery Miles 25 180 Save R1,051 (29%) Ships in 7 - 13 working days

The incidence of autoimmune diseases is increasing worldwide, and the search for better management of these diseases and even for a cure is being pursued by scientists from many disciplines. Tools from the areas of genetics, neuroscience, cell biology, virology, and infectious disease are being applied to the problem and are yielding useful results.

This is the fourth and final volume of a series on autoimmunity, and findings related to particular clinical manifestations are presented, particularly systemic lupus erythematosus, scleroderma, rheumatoid arthritis, Sjogren's syndrome, antiphospholipid antibodies, and infections and autoantibodies.

Part A presents new principles in autoimmunity and new diagnostic tools; Part B focuses on genetics and advances in treatment; and Part C begins the focus on the clinical venue.

"NOTE: Annals volumes are available for sale as individual books or as a journal. For information on institutional journal subscriptions, please visit ""www.blackwellpublishing.com/nyas,"" "

"ACADEMY MEMBERS: Please contact the New York Academy of Sciences directly to place your order (""www.nyas.org""). Members of the New York Academy of Science receive full-text access to the Annals online and discounts on print volumes. Please visit ""www.nyas.org/membership/main.asp"" for more information about becoming a member.
"

Autoimmunity, Part A - Basic Principles and New Diagnostic Tools, Volume 1109 (Paperback, New): M.E. Gershwin, Yehuda Shoenfeld Autoimmunity, Part A - Basic Principles and New Diagnostic Tools, Volume 1109 (Paperback, New)
M.E. Gershwin, Yehuda Shoenfeld
R3,563 R2,513 Discovery Miles 25 130 Save R1,050 (29%) Ships in 7 - 13 working days

The incidence of autoimmune diseases is increasing worldwide, and the search for better management of these diseases and even for a cure is being pursued by scientists from many disciplines. Tools from the areas of genetics, neuroscience, cell biology, virology, and infectious disease are being applied to the problem and are yielding useful results.

This volume contains the first section of the proceedings of a large, comprehensive meeting held in Sorrento, Italy. Because the meeting focused on such an important area of human health, four volumes have been dedicated to it: Part A presents new principles in autoimmunity, including the roles of key players such as designed ankyrin repeat proteins, SLAM-associated protein, interleukin-12, human proteinase 3, the complement system, IgG, disturbances in cytokine synthesis, and IFN-γ blockers. The second section of the volume takes a look at new diagnostic tools, including screening of endothelial expression libraries, electrical skin impedance, and IgA anti-tissue transglutaminase antibody assays.

"Autoimmunity, Part B" continues the presentation of basic research and its applications with a focus on genetics. Parts C and D present the clinical research in various manifestations of autoimmune disease and its treatments.

"NOTE: Annals volumes are available for sale as individual books or as a journal. For information on institutional journal subscriptions, please visit ""www.blackwellpublishing.com/nyas,"" "

"ACADEMY MEMBERS: Please contact the New York Academy of Sciences directly to place your order (""www.nyas.org""). Members of the New York Academy of Science receive full-text access to the Annals online anddiscounts on print volumes. Please visit ""www.nyas.org/membership/main.asp"" for more information about becoming a member.
"

Autoimmune Diseases and Treatment - Organ-Specific and Systemic Disorders, Volume 1051 (Paperback): Yehuda Shoenfeld, M.E.... Autoimmune Diseases and Treatment - Organ-Specific and Systemic Disorders, Volume 1051 (Paperback)
Yehuda Shoenfeld, M.E. Gershwin
R3,695 R2,607 Discovery Miles 26 070 Save R1,088 (29%) Ships in 7 - 13 working days

Only in very recent times have therapies been developed that are specific to a particular manifestation of autoimmune disease, and these have begun to replace the all-purpose remedies of the past 30 years. This volume, which draws on the principles of immunology presented in Volume 1050 ("Autoimmunity: Concepts and Diagnosis at the Cutting Edge"), extends these concepts to the realm of clinical findings and current therapy for many autoimmune and connective tissue disorders.

Both organ-specific and organ-nonspecific diseases are covered, and one section is entirely focused on treatment. Treatments using cytokines, chemokines, cognate receptors, and genetic interactions are particularly prominent in these reports, and attention is also paid to the increasing use of intravenous imunoglobulins and both monoclonal and imunosuppressive agents. A therapeutic void remains, but the work reported on here contributes considerably to the effort to fill that void.

"NOTE: Annals volumes are available for sale as individual books or as a journal. For information on institutional journal subscriptions, please visit" "www.blackwellpublishing.com/nyas".""

"ACADEMY MEMBERS Please contact the New York Academy of Sciences directly to place your order (""www.nyas.org""). Members of the New York Academy of Science receive full-text access to the Annals online and discounts on print volumes. Please visit http: //www.nyas.org/MemberCenter/Join.aspx for more information about becoming a member."

The Antiphospholipid Syndrome II - Autoimmune Thrombosis (Hardcover, 2nd ed.): Ricardo Cubedo Cervera, Ronald A. Asherson, J.C.... The Antiphospholipid Syndrome II - Autoimmune Thrombosis (Hardcover, 2nd ed.)
Ricardo Cubedo Cervera, Ronald A. Asherson, J.C. Piette, Yehuda Shoenfeld
R5,275 R4,339 Discovery Miles 43 390 Save R936 (18%) Ships in 10 - 15 working days

This book provides the reader with a comprehensive overview of the Antiphospholipid syndrome. One of the most important advances in rheumatology and connective tissue diseases of the last decade. It provides an explanation for many previously undefined conditions with no clear pathogenesis encompassing all subspeculations in internal medicine as well as obstetrics. Clotting problems leading to strokes and myocardial infarctions (in younger people) as well as a large variety of other syndromes such as chorea, hyproadrenalism, pulmonary problems are now being understood.

Contemporary Challenges in Autoimmunity, Volume 1173 (Paperback, New): Yehuda Shoenfeld, M.E. Gershwin Contemporary Challenges in Autoimmunity, Volume 1173 (Paperback, New)
Yehuda Shoenfeld, M.E. Gershwin
R3,629 R2,578 Discovery Miles 25 780 Save R1,051 (29%) Ships in 7 - 13 working days

This volume features key presentations from the 6th International Congress of Autoimmunity. The International Congress of Autoimmunity has become established as one of the major meetings in the field of immunology, with presentations covering every aspect of basic research in the hopes of clarifying pathogenesis of autoimmune disease as well as providing information on the latest innovations in biological and other modes of treatment. The goal of this volume is to present cutting edge research that focuses in particular on newer diagnostic tools and newer therapies for human autoimmune disease.

"NOTE: Annals volumes are available for sale as individual books or as a journal. For information on institutional journal subscriptions, please visit" "www.blackwellpublishing.com/nyas".""

"ACADEMY MEMBERS: Please contact the New York Academy of Sciences directly to place your order (""www.nyas.org""). Members of the New York Academy of Science receive full-text access to the Annals online and discounts on print volumes. Please visit http: //www.nyas.org/MemberCenter/Join.aspx for more information about becoming a member."

Autoimmunity, Part B - Novel Applications of Basic Research (Paperback): M.E. Gershwin, Yehuda Shoenfeld Autoimmunity, Part B - Novel Applications of Basic Research (Paperback)
M.E. Gershwin, Yehuda Shoenfeld
R3,578 R2,527 Discovery Miles 25 270 Save R1,051 (29%) Ships in 7 - 13 working days

The incidence of autoimmune diseases is increasing worldwide, and the search for better management of these diseases and even for a cure is being pursued by scientists from many disciplines. Tools from the areas of genetics, neuroscience, cell biology, virology, and infectious disease are being applied to the problem and are yielding useful results.

This is the second volume of a series of four on autoimmunity, and findings related to particular organs, organ systems, and diseases are presented. The focus in Part B is on genetics and advances in treatment. Part A presents new principles in autoimmunity and new diagnostic tools. See Parts C and D for clinical venues in autoimmunity.

"NOTE: Annals volumes are available for sale as individual books or as a journal. For information on institutional journal subscriptions, please visit ""www.blackwellpublishing.com/nyas,"" "

"ACADEMY MEMBERS: Please contact the New York Academy of Sciences directly to place your order (""www.nyas.org""). Members of the New York Academy of Science receive full-text access to the Annals online and discounts on print volumes. Please visit ""www.nyas.org/membership/main.asp"" for more information about becoming a member.
"

Mosaic of Autoimmunity - The Novel Factors of Autoimmune Diseases (Paperback): Carlo Perricone, Yehuda Shoenfeld Mosaic of Autoimmunity - The Novel Factors of Autoimmune Diseases (Paperback)
Carlo Perricone, Yehuda Shoenfeld
R4,035 R3,827 Discovery Miles 38 270 Save R208 (5%) Ships in 10 - 15 working days

The Mosaic of Autoimmunity: The Novel Factors of Autoimmune Diseases describes the multifactorial origin and diversity of expression of autoimmune diseases in humans. The term implies that different combinations of factors in autoimmunity produce varying and unique clinical pictures in a wide spectrum of autoimmune diseases. Most of the factors involved in autoimmunity can be categorized into four groups: genetic, immune defects, hormonal and environmental factors. In this book, the environmental factors are reviewed, including infectious agents, vaccines as triggers of autoimmunity, smoking and its relationship with rheumatoid arthritis, systemic lupus erythematosus, thyroid disease, multiple sclerosis and inflammatory bowel diseases. An entirely new syndrome, the autoimmune/inflammatory syndrome induced by adjuvants (ASIA), is also included, along with other diseases that are now recognized as having an autoimmune etiopathogenesis.

Cancer and Autoimmunity (Hardcover): Yehuda Shoenfeld, M.E. Gershwin Cancer and Autoimmunity (Hardcover)
Yehuda Shoenfeld, M.E. Gershwin
R9,582 Discovery Miles 95 820 Out of stock

Of the two disciplines in parallel development for two decades, tumor immunology and transplantation immunology, the latter has thrived and has led to some of the most critical discoveries in immunobiology. The former continues to thwart both scientists and clinicians alike.
The goal of immunologists in modern day research is to develop a simple and effective means to manipulate cancer "in vivo, " possibly encompassing several venues: identifying a phenotypic marker and the use of either active or passive immunization; include the use of passive reagents carrying "warheads" to selectively destroy cancer cells; or altering the basic process of cell survival.
This excellent multidiscipline-authored volume presents a theme which has not been well described before. The papers include both basic and clinical science and range from sophisticated molecular biology to little more than phenomenology (e.g. the increased association of cancer in some autoimmune diseases and increased presentation of autoimmune phenomena in malignant condition). This, however, is state-of-the-art.
This collection of themes will be of use not only to bench scientists, but also to clinicians who treat patients. The book represents progress at the cutting edge of this discipline, and points the way to further developments in the "black box" of immunology.

Autoimmunity, Part C - The Mosaic of Autoimmunity, Volume 1107 (Paperback): Yehuda Shoenfeld, M.E. Gershwin Autoimmunity, Part C - The Mosaic of Autoimmunity, Volume 1107 (Paperback)
Yehuda Shoenfeld, M.E. Gershwin
R3,261 Discovery Miles 32 610 Out of stock

The incidence of autoimmune diseases is increasing worldwide, and the search for better management of these diseases and even for a cure is being pursued by scientists from many disciplines. Tools from the areas of genetics, neuorscience, cell biology, virology, and infectious disease are being applied to the problem and are yielding useful results.

This is the third volume of a series of four on autoimmunity, and findings related to particular organs, organ systems, and diseases are presented. The focus in Part C is on autoimmunity and vessel pathology, the neurologic system, cancer, the GI tract, diabetes, the lung, and the heart.

"Autoimmunity, Part D" completes the group of volumes and also presents research focusing on clinical manifestations of autoimmunity. See Parts A and B for basic research findings.

"NOTE: Annals volumes are available for sale as individual books or as a journal. For information on institutional journal subscriptions, please visit ""www.blackwellpublishing.com/nyas,"" "

"ACADEMY MEMBERS: Please contact the New York Academy of Sciences directly to place your order (""www.nyas.org""). Members of the New York Academy of Science receive full-text access to the Annals online and discounts on print volumes. Please visit ""www.nyas.org/membership/main.asp"" for more information about becoming a member.
"

Diagnostic Criteria in Autoimmune Diseases (Hardcover, 2008 ed.): Ricard Cervera, M.E. Gershwin, Yehuda Shoenfeld Diagnostic Criteria in Autoimmune Diseases (Hardcover, 2008 ed.)
Ricard Cervera, M.E. Gershwin, Yehuda Shoenfeld
R7,479 R7,065 Discovery Miles 70 650 Save R414 (6%) Out of stock

According to the Autoimmune Diseases Coordinating Committee (ADCC), between 14.7 and 23.5 million people in the USA up to eight percent of the population are affected by autoimmune disease. Autoimmune diseases are a family of more than 100 chronic, and often disabling, illnesses that develop when underlying defects in the immune system lead the body to attack its own organs, tissues, and cells. In Handbook of Autoimmune Disease, the editors have gathered in a comprehensive handbook a critical review, by renowned experts, of more than 100 autoimmune diseases, divided into two main groups, namely systemic and organ-specific autoimmune diseases. A contemporary overview of these conditions with special emphasis on diagnosis is presented. Each chapter contains the essential information required by attending physicians as well as bench scientists to understand the definition of a specific autoimmune disease, the diagnostic criteria, and the treatment.

Diagnostic Criteria in Autoimmune Diseases (Paperback, 2008 ed.): Ricard Cervera, M.E. Gershwin, Yehuda Shoenfeld Diagnostic Criteria in Autoimmune Diseases (Paperback, 2008 ed.)
Ricard Cervera, M.E. Gershwin, Yehuda Shoenfeld
R5,294 R5,005 Discovery Miles 50 050 Save R289 (5%) Out of stock

According to the Autoimmune Diseases Coordinating Committee (ADCC), between 14.7 and 23.5 million people in the USA - up to eight percent of the population are affected by autoimmune disease. Autoimmune diseases are a family of more than 100 chronic, and often disabling, illnesses that develop when underlying defects in the immune system lead the body to attack its own organs, tissues, and cells. In Handbook of Autoimmune Disease, the editors have gathered in a comprehensive handbook a critical review, by renowned experts, of more than 100 autoimmune diseases, divided into two main groups, namely systemic and organ-specific autoimmune diseases. A contemporary overview of these conditions with special emphasis on diagnosis is presented. Each chapter contains the essential information required by attending physicians as well as bench scientists to understand the definition of a specific autoimmune disease, the diagnostic criteria, and the treatment.

Idiotypes in Medicine: Autoimmunity, Infection and Cancer (Hardcover): R.C. Kennedy, S. Ferrone, Yehuda Shoenfeld Idiotypes in Medicine: Autoimmunity, Infection and Cancer (Hardcover)
R.C. Kennedy, S. Ferrone, Yehuda Shoenfeld
R8,167 R7,699 Discovery Miles 76 990 Save R468 (6%) Out of stock

This is the most comprehensive review of the idiotypic network available. All the current knowledge of idiotypes of the various antibodies is incorporated in this volume. The pathogenic role of idiotypes in autoimmunity and cancer is reviewed in depth. The therapeutic part focusses on harnessing anti-idiotypes for treating autoimmunological disorders, and on the employment of idiotypes for vaccines in cancer and infectious diseases, as well as explaining the manipulation of the idiotypic network in autoimmunity and cancer idiotypes and vaccines.

The Decade of Autoimmunity (Hardcover): Yehuda Shoenfeld The Decade of Autoimmunity (Hardcover)
Yehuda Shoenfeld
R5,991 R5,657 Discovery Miles 56 570 Save R334 (6%) Out of stock

This book is a direct result of 10 years of the well-known "Autoimmunity Days" in Israel, which are increasingly becoming an international focal point for autoimmunity scientists. Top researchers provide coverage of the most important knowledge generated during the last decade. The volume can therefore be seen almost as a textbook on autoimmunity, projecting from the last decade to the next millennium.
A variety of different subjects in autoimmunity, from etiology to pathogenesis, from postulated mechanisms to innovative therapeutic modalities, is handled by noted contributors, while additional authors contribute top papers which significantly enhance a better understanding of autoimmunity.
An excellent treatise on the subject, and a worthwhile addition to both clinical and research libraries.

Infection and Autoimmunity (Hardcover, 2nd edition): Yehuda Shoenfeld, Nancy Agmon Levin, Noel R. Rose Infection and Autoimmunity (Hardcover, 2nd edition)
Yehuda Shoenfeld, Nancy Agmon Levin, Noel R. Rose
R5,221 Discovery Miles 52 210 Out of stock

Autoimmune diseases are conditions where the immune system attacks the body organs instead of foreign invaders. This book deals with the various mechanisms by which infectious agents can trigger autoimmunity such as molecular mimicry and polyclonal activation. An overview is given with regard to bacteria, viruses, and parasites associated with autoimmunity, and a summary is given on classical autoimmune diseases and the infecting agents that can induce them.

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