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Books > Medicine > Clinical & internal medicine > Diseases & disorders > Oncology

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Genetic Immunization (Paperback, 1st ed. Softcover of orig. ed. 2000) Loot Price: R2,771 Discovery Miles 27 710 You Save: R162 (6%)
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Genetic Immunization (Paperback, 1st ed. Softcover of orig. ed. 2000): Adrian Bot, Constantin A. Bona
Genetic Immunization (Paperback, 1st ed. Softcover of orig. ed. 2000): Adrian Bot, Constantin A. Bona

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Genetic Immunization (Paperback, 1st ed. Softcover of orig. ed. 2000)

Adrian Bot, Constantin A. Bona

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List price R2,933 Loot Price R2,771 Discovery Miles 27 710 You Save R162 (6%)

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Wolf's discovery demonstrating that a reporter gene is expressed in myocytes subsequent to injection of naked DNA, was exploited by immunologists and vaccinologists to develop a new generation of vaccines. This observation galvanized the research and in a short lapse of time, an oceanic volume of knowledge has been accumulated. The research carried out in a variety of animal models showed the efficacy of genetic immunization against viruses, bacteria, and some parasites by the ability to induce a strong priming effect resulting from long-lasting persistence of plasmid as episomes. Furthermore, it was demonstrated that newborn or infant immune unresponsiveness to classical vaccines can be corrected by genetic immunization. The applications of genetic immunization for prophylaxis of infections was extended to immunotherapy, namely, cancerous, auto- immune, and allergic diseases. Immunologists have provided pertinent information on the cellular basis of the immune responses elicited by genetic immunization, and molecular biologists have established the molecular basis of intrinsic adjuvant properties of plasmids.

General

Imprint: Springer-Verlag New York
Country of origin: United States
Release date: October 2010
First published: 2000
Authors: Adrian Bot • Constantin A. Bona
Dimensions: 178 x 254 x 10mm (L x W x T)
Format: Paperback - Trade
Pages: 180
Edition: 1st ed. Softcover of orig. ed. 2000
ISBN-13: 978-1-4419-3327-0
Barcode: 9781441933270
Categories: Promotions
Books > Medicine > Clinical & internal medicine > Diseases & disorders > Immunology > Allergies
Books > Medicine > Other branches of medicine > Pathology > Medical microbiology & virology
Books > Medicine > Clinical & internal medicine > Diseases & disorders > Oncology
Books > Medicine > Clinical & internal medicine > Diseases & disorders > Oncology > General
Books > Medicine > General issues > Public health & preventive medicine
Books > Medicine > General issues > Public health & preventive medicine > General
LSN: 1-4419-3327-1

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