Up-to-date summary of biochemistry and pharmacology of COMT and its inhibitors Preclinical models in COMT inhibitor devlopment Transgenic COMT mice latest information summarized Chemistry of COMT inhibitors and their design with molecular modelling COMT gene and its regulation and relation to dopamine related diseases Role of cofactor SAM regulation in relation to homocysteine Nonclinical and clinical safety of COMT inhibitors summarized Future prospects of COMT inhibitors in Parkinson s disease
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Up-to-date summary of biochemistry and pharmacology of COMT and its inhibitors Preclinical models in COMT inhibitor devlopment Transgenic COMT mice latest information summarized Chemistry of COMT inhibitors and their design with molecular modelling COMT gene and its regulation and relation to dopamine related diseases Role of cofactor SAM regulation in relation to homocysteine Nonclinical and clinical safety of COMT inhibitors summarized Future prospects of COMT inhibitors in Parkinson s disease
Imprint | Academic Press Inc |
Country of origin | United States |
Series | International Review of Neurobiology |
Release date | December 2010 |
Availability | Expected to ship within 10 - 15 working days |
First published | December 2010 |
Volume editors | Erkki Nissinen |
Dimensions | 229 x 152 x 19mm (L x W x T) |
Format | Hardcover |
Pages | 336 |
Edition | 94th edition |
ISBN-13 | 978-0-12-381326-8 |
Barcode | 9780123813268 |
Categories | |
LSN | 0-12-381326-3 |