Atrial natriuretic peptide (ANP), atrial natriuretic factor (ANF),
atrial natriuretic hormone (ANH), or atriopeptin, is a powerful
vasodilator, and a protein (polypeptide) hormone secreted by heart
muscle cells. It is involved in the homeostatic control of body
water, sodium, potassium and fat (adipose tissue). It is released
by muscle cells in the upper chambers (atria) of the heart (atrial
myocytes), in response to high blood pressure. ANP acts to reduce
the water, sodium and adipose loads on the circulatory system,
thereby reducing blood pressure.
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