reached full definition in the 1940s by Kempner diet. The important
role of adrenal aldosterone and associates in demonstrating the
beneficial ef- secretion in supporting human hypertension is now
fects of a low salt rice diet for treating hypertensive well
recognized as are the beneficial effects of patients. It became
apparent that the value of rice blockade, especially in low-renin
patients who ex- was wholly related to its sodium content. A rice
hibit inappropriate or absolute excesses of aldoste- diet, or any
other stringent low sodium diet, rone secretion. Further definition
of the more sub- greatly improves or completely corrects the hyper-
tle participation of aldosterone and of the factors tension of
about ~ or so of all patients with essen- that control aldosterone
secretion in hypertensive subjects are promising areas for further
research. tial hypertension. However, what is often forgotten is
that little or no benefit accrues to the remaining THE NERVOUS
SYSTEM majority of patients. Parallel studies of animal models has
demon- Besides the endocrine and excretory functions of strated the
amplifying effect of a high sodium diet the kidney and the
influence of dietary sodium on blood pressure and vice versa.
Strains of rats and of aldosterone secretion, there has been long-
were developed which are especially sensitive to standing agreement
about the important role of the pressor effects of a high sodium
diet. In a way, the nervous system in blood pressure control.
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