Books > Science & Mathematics > Chemistry > Organic chemistry
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Lambert M. Surhone, Miriam T. Timpledon, Susan F. Marseken, Surhone Lambert M., Tennoe Mariam T., Henssonow Susan F.
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Pyrazole refers both to the class of simple aromatic ring organic
compounds of the heterocyclic series characterized by a 5-membered
ring structure composed of three carbon atoms and two nitrogen
atoms in adjacent positions, and to the unsubstituted parent
compound. Being so composed and having pharmacological effects on
humans, they are classified as alkaloids, although they are rare in
nature. In a classical method developed by H. Pechmann in 1898
pyrazole is synthesized from acetylene and diazomethane. In
medicine, pyrazoles are used for their analgesic,
anti-inflammatory, antipyretic, antiarrhythmic, tranquilizing,
muscle relaxing, psychoanaleptic, anticonvulsant, monoamineoxidase
inhibiting, antidiabetic and antibacterial activities. Pyrazoles
react with potassium borohydride to form a class of ligands known
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