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Tubulin alpha-4A chain is a protein that in humans is encoded by
the TUBA4A gene.Microtubules of the eukaryotic cytoskeleton perform
essential and diverse functions and are composed of a heterodimer
of alpha and beta tubulin. The genes encoding these microtubule
constituents are part of the tubulin superfamily, which is composed
of six distinct families. Genes from the alpha, beta and gamma
tubulin families are found in all eukaryotes. The alpha and beta
tubulins represent the major components of microtubules, while
gamma tubulin plays a critical role in the nucleation of
microtubule assembly. There are multiple alpha and beta tubulin
genes and they are highly conserved among and between species. This
gene encodes an alpha tubulin that is a highly conserved homolog of
a rat testis-specific alpha tubulin.
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