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Books > Medicine > Clinical & internal medicine > Diseases & disorders > Oncology

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New Developments in Metastasis Suppressor Research (Hardcover, Illustrated Ed) Loot Price: R1,709 Discovery Miles 17 090 You Save: R137 (7%)

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New Developments in Metastasis Suppressor Research (Hardcover, Illustrated Ed): Paul Jackson
New Developments in Metastasis Suppressor Research (Hardcover, Illustrated Ed): Paul Jackson

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New Developments in Metastasis Suppressor Research (Hardcover, Illustrated Ed)

Paul Jackson

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List price R1,846 Loot Price R1,709 Discovery Miles 17 090 You Save R137 (7%)

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The spread of cancer cells from their organ of origin to distant tissues is called metastasis. Cancer metastasis is the main cause of death from cancer, and in many cases is difficult to detect or treat. The process by which tumour cells become metastatic is complex and involves many stages, including detachment of cells from the main tumour mass, degradation of the surrounding extra-cellular matrix, invasion into nearby blood vessels, travel and survival through the circulatory system, attachment to a vessel wall, extra-vasation, degradation of the extra-cellular matrix into a distant tissue/organ, and the development of a novel blood supply. In order to accomplish this process, the cells acquire characteristics which are important for each stage. Recently, a class of genes known as metastasis suppressors' has been the subject of intense investigation. For some metastasis suppressor genes, there is strong evidence from both in vitro and in vivo studies to demonstrate key roles in the metastatic process, for others data is much more limited, and their importance uncertain. In this book, chapters are devoted to providing up-to-date summaries of our understanding of individual metastasis suppressor genes. Each is written by a leading authority in the study of that gene. Topics covered include discussions on how each metastasis suppressor was discovered, the mechanisms underlying their loss of expression in tumours and tumour cell lines, their proposed molecular functions, and the consequences to a tumour cell of the loss of this function. This compilation aims to provide, in a single volume, comprehensive information that will be valuable to all scientists working in cancer research, to students needing to understand molecular events that regulate tumour progression and the acquisition of metastasis, and to clinicians who might wish to know more of the roles of potentially new markers for cancer diagnosis and prognosis.

General

Imprint: nova science publishers
Country of origin: United States
Release date: September 2007
Editors: Paul Jackson
Dimensions: 180 x 260 x 33mm (L x W x T)
Format: Hardcover
Pages: 328
Edition: Illustrated Ed
ISBN-13: 978-1-60021-603-9
Barcode: 9781600216039
Categories: Books > Medicine > General issues > Medical equipment & techniques > Medical research
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Books > Medicine > Clinical & internal medicine > Diseases & disorders > Oncology
Books > Medicine > Clinical & internal medicine > Diseases & disorders > Oncology > General
LSN: 1-60021-603-X

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