Norepinephrine Reuptake Inhibitors - Norepinephrine-Dopamine Reuptake Inhibitors, Serotonin-Norepinephrine-Dopamine Reuptake Inhibitors, Cocaine (Paperback)

Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. Pages: 82. Chapters: Norepinephrine-dopamine reuptake inhibitors, Serotonin-norepinephrine-dopamine reuptake inhibitors, Cocaine, Amphetamine, Bupropion, Methylphenidate, Tramadol, Venlafaxine, Serotonin-norepinephrine-dopamine reuptake inhibitor, Atomoxetine, Tapentadol, Amineptine, Methylenedioxypyrovalerone, Maprotiline, Dexmethylphenidate, Norepinephrine reuptake inhibitor, Phenyltropane, Tesofensine, Hyperforin, Nefopam, Reboxetine, Naphyrone, PRC200, Tametraline, Indatraline, JNJ-7,925,476, Brasofensine, Desoxypipradrol, Dichloropane, Lortalamine, Radafaxine, Diphenylprolinol, Nomifensine, Diclofensine, LR-5182, Amoxapine, Lefetamine, Prolintane, Amedalin, Fencamfamine, Daledalin, Difemetorex, Talopram, Esreboxetine, Manifaxine, Talsupram, Psoralea corylifolia, 2 -Propanoyl-3 -(4-tolyl)-tropane, Adhyperforin, Cilobamine, NS-2359, Fencamine, GSK1360707F, 2 -Propanoyl-3 -(2-naphthyl)-tropane, D-161. Excerpt: Cocaine (benzoylmethylecgonine) (INN) is a crystalline tropane alkaloid that is obtained from the leaves of the coca plant. The name comes from "coca" in addition to the alkaloid suffix -ine, forming cocaine. It is a stimulant of the central nervous system, an appetite suppressant, and a topical anesthetic. Specifically, it is a serotonin-norepinephrine-dopamine reuptake inhibitor, which mediates functionality of these neurotransmitters as an exogenous catecholamine transporter ligand. Because of the way it affects the mesolimbic reward pathway, cocaine is addictive. Unlike most molecules, cocaine possesses both high hydrophilic and lipophilic efficiency, violating the rule of hydrophilic-lipophilic balance. This causes it to cross the blood-brain barrier with vastly superior reinforcement than to other psychoactive chemicals. Its possession, cultivation, and distribution are illegal for non-medicinal and non-government sanction...