Epigenetics is considered by many to be the "new genetics"
because the realization that many biological phenomena are
controlled not through gene mutations, but rather through
reversible and heritable epigenetic processes that have opened up
new paths for discovery. The biological processes impacted by
epigenetics range from tissue/organ regeneration, X-chromosome
inactivation, and stem cell differentiation to genomic imprinting
and aging. The effects of epigenetics are vast and encompass lower
organisms as well as humans. Aberrations of epigenetics influence
many diseases involving but not limited to cancer, immune
disorders, neurological and metabolic disorders, and imprinting
diseases. Clinical intervention is already in place for some of
these disorders and many novel epigenetic therapies are on the
This comprehensive collection of reviews written by leaders in
the field of epigenetics provides a broad view of this important
and evolving topic. From molecular mechanisms and epigenetic
technology to discoveries in human disease and clinical epigenetics
the nature and applications of the science will be presented for
those with interests ranging from the fundamental basis of
epigenetics to therapeutic interventions for epigenetic-based
* Contributions by leading international investigators involved
in molecular research and clinical and therapeutic applications
* Integrates methods and biological topics with basic and
* Includes coverage of new topics in epigenetics such as prions,
regulation of long-term memory by epigenetics, metabolic aspects of
epigenetics, and epigenetics of neuronal disorders
Academic Press Inc
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||Electronic book text - Windows
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