Advances in Genetics, Volume 36 (Hardcover)

This volume continues to present articles which should be of interest to both human and molecular geneticists. It begins with a review of the various classifications, mechanisms and molecular diagnostic tests of peroneal muscular atrophy (or CMT). An examination of the importance of tumour suppressor genes in human cancer and a number of the significant problems faced by cancer geneticists is included. The notion of genetic redundancy and whether true functional redundancy can exist is investigated and a discussion of recent findings on speciation and the role of hybrid inviability in "drosophila" is conducted. This book also reviews the effects of metal-regulated gene expression in cellular metabolism, pathogenicity and toxicity. In addition, it provides descriptions of chromosomal translocations in Neuraospora and other fungi for use in executing genetic crosses.