The development of a bio-engineered pacemaker is of substantial
clinical and also scientific interest because it promises to
overcome several limitations of electronic pacemakers. Moreover it
may answer the longstanding question of whether the complex
structure of the sinus node is indeed a prerequisite for reliable
pacemaking, or simpler structures might work as well.
This book gives an overview of the current state-of-the-art of
creating a bio-engineered pacemaker. It shows the approaches to
develop of genetic and cell-based engineering methods suitable to
implement them with safety and stability. It also illuminates the
problems that need to be solved before bio-pacemaking can be
considered for clinical use.
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