The Maillard reaction, which has been at the crossroads of food and biomedical sciences, is now also known to contribute to the natural and normal aging of tissue proteins and other biomolecules. It is also implicated in the pathologic processes of a range of age-related chronic diseases, including arthritis, atherosclerosis, diabetes, and neurodegenerative diseases. The role of the Maillard reaction in diabetes and its complications has become a major focus of research, leading to a better understanding of the importance of oxidative stress, lipid peroxidation, and hyperlipidemia in diabetic complications.
This volume addresses all of these issues - -from food to biomedical sciences -- and highlights current research trends, including the identification of new biomarkers, nutrition, and toxicology, and the role of oxidative stress, advanced glycoxidation and lipoxidation end products (AGE/ALEs) in aging and chronic disease.
The last section of the book, devoted to recent research on AGE/ALE inhibitors in animal models and clinical trials, assesses the current status of pharmaceutical interventions for retarding the Maillard reaction and the pathophysiology associated with aging and age-related disease.
"NOTE: Annals volumes are available for sale as individual books or as a journal. For information on institutionaljournal subscriptions, please visit www.blackwellpublishing.com/nyas. "
"ACADEMY MEMBERS: Please contact the New York Academy of Sciences directly to place your order (www.nyas.org). Members of the New York Academy of Science receive full-text access to the Annals online and discounts on print volumes. Please visit www.nyas.org/membership/main.asp for more information about becoming a member."
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The Maillard reaction, which has been at the crossroads of food and biomedical sciences, is now also known to contribute to the natural and normal aging of tissue proteins and other biomolecules. It is also implicated in the pathologic processes of a range of age-related chronic diseases, including arthritis, atherosclerosis, diabetes, and neurodegenerative diseases. The role of the Maillard reaction in diabetes and its complications has become a major focus of research, leading to a better understanding of the importance of oxidative stress, lipid peroxidation, and hyperlipidemia in diabetic complications.
This volume addresses all of these issues - -from food to biomedical sciences -- and highlights current research trends, including the identification of new biomarkers, nutrition, and toxicology, and the role of oxidative stress, advanced glycoxidation and lipoxidation end products (AGE/ALEs) in aging and chronic disease.
The last section of the book, devoted to recent research on AGE/ALE inhibitors in animal models and clinical trials, assesses the current status of pharmaceutical interventions for retarding the Maillard reaction and the pathophysiology associated with aging and age-related disease.
"NOTE: Annals volumes are available for sale as individual books or as a journal. For information on institutionaljournal subscriptions, please visit www.blackwellpublishing.com/nyas. "
"ACADEMY MEMBERS: Please contact the New York Academy of Sciences directly to place your order (www.nyas.org). Members of the New York Academy of Science receive full-text access to the Annals online and discounts on print volumes. Please visit www.nyas.org/membership/main.asp for more information about becoming a member."
Imprint | New York Academy of Sciences |
Country of origin | United States |
Series | Annals of the New York Academy of Sciences, v. 1043 |
Release date | July 2005 |
Availability | Supplier out of stock. If you add this item to your wish list we will let you know when it becomes available. |
First published | August 2005 |
Editors | John W. Baynes, Vincent M. Monnier, Jennifer M. Ames, Suzanne Thorpe |
Dimensions | 230 x 152mm (L x W) |
Format | Paperback |
Pages | 956 |
ISBN-13 | 978-1-57331-532-6 |
Barcode | 9781573315326 |
Categories | |
LSN | 1-57331-532-X |