Ercc2 (Paperback)

Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. ERCC2, or XPD is a protein involved in transcription-coupled nucleotide excision repair.The XPD (ERCC2) gene encodes for a 2.3-kb mRNA containing 22 exons and 21 introns. The XPD protein is a 760 amino acids polypeptide with a size of 87kDa. Defects in this gene can result in three different disorders: the cancer-prone syndrome xeroderma pigmentosum complementation group D, trichothiodystrophy, and Cockayne syndrome.