Small Nucleolar RNA Snora67 (Paperback)

High Quality Content by WIKIPEDIA articles snoRNA U67 is a non-coding RNA molecule that belongs to the H/ACA class of snoRNAs which are thought to guide the sites of modification of uridines to pseudouridines. This snoRNA guides pseudouridylation of position U1445 in 18S rRNA. This RNA is expressed from the intron of the host gene EIF4A1. Small nucleolar RNAs (snoRNAs) are a class of small RNA molecules that primarily guide chemical modifications of other RNAs, mainly ribosomal RNAs, transfer RNAs and small nuclear RNAs. There are two main classes of snoRNA, the C/D box snoRNAs which are associated with methylation, and the H/ACA box snoRNAs which are associated with pseudouridylation. snoRNAs are commonly referred to as guide RNAs but should not be confused with the guide RNAs that direct RNA editing in trypanosomes.