Tpsd1 (Paperback)

Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. Tryptase delta is an enzyme that in humans is encoded by the TPSD1 gene.Tryptases comprise a family of trypsin-like serine proteases, the peptidase family S1. Tryptases are enzymatically active only as heparin-stabilized tetramers, and they are resistant to all known endogenous proteinase inhibitors. Several tryptase genes are clustered on chromosome 16p13.3. These genes are characterized by several distinct features. They have a highly conserved 3' UTR and contain tandem repeat sequences at the 5' flank and 3' UTR which are thought to play a role in regulation of the mRNA stability.