This volume provides an overview of the latency strategies developed during the estimated 200 Myears long coevolution of Alpha-, Beta- and Gammaherpesvirinae and their host species. The main emphasis is on herpesviruses infecting humans. However, relevant cases if herpesviruses infecting animals are covered as well. Special emphasis is drawn on results on molecular mechanisms regulating latent promoters of herpesvirus genomes and signals and molecular pathways resulting in reactivation of latent viral genomes. To balance the volume, epigenetic mechanisms (DNA methylation, histone modification, chromatin structure) involved in cell type specific expression of growth-transformation-associated Gammaherpesvirus genes will also be discussed at length)
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This volume provides an overview of the latency strategies developed during the estimated 200 Myears long coevolution of Alpha-, Beta- and Gammaherpesvirinae and their host species. The main emphasis is on herpesviruses infecting humans. However, relevant cases if herpesviruses infecting animals are covered as well. Special emphasis is drawn on results on molecular mechanisms regulating latent promoters of herpesvirus genomes and signals and molecular pathways resulting in reactivation of latent viral genomes. To balance the volume, epigenetic mechanisms (DNA methylation, histone modification, chromatin structure) involved in cell type specific expression of growth-transformation-associated Gammaherpesvirus genes will also be discussed at length)
Imprint | Springer-Verlag New York |
Country of origin | United States |
Release date | October 2006 |
Availability | Expected to ship within 10 - 15 working days |
First published | 2007 |
Editors | Janos Minarovits, Eva Gonczol, Tibor Valyi-nagy |
Dimensions | 235 x 155 x 19mm (L x W x T) |
Format | Hardcover |
Pages | 300 |
Edition | 2007 ed. |
ISBN-13 | 978-0-387-32464-7 |
Barcode | 9780387324647 |
Categories | |
LSN | 0-387-32464-X |