Sodium in Health and Disease (Hardcover)

report on the latest developments in the field with new information in basic as well as in clinical sciences, S"odium in Health Diseases," covers both the physiology of sodium balance and how it relates to disease. Expertly written, its concise text examines ATPase, transport and receptor systems, and sodium balance as it relates to sex hormones, genes, and body fluid. This text will also examine disease based on animal models, genetic disorders, and the influence of sodium on pulse pressure, isolated systolic hypertension, and its blood pressure sensitivity.

"Sodium in Health and Disease" will

- cover the newest data on sodium transport by the epithelial sodium channel or the impact of renal structure proteins on sodium transport

- discuss the latest developments in our understanding of the role of aldosterone and 11-beta-hydroxysteroid dehydrogenase in the regulation of sodium balance.

- present original observations on the role of salt in isolated systolic hypertension and in the development of arterial stiffness.

- give new data on renal sodium handling in women and in diabetes and the metabolic syndrome.

Important topics covered:

- the epithelial sodium channel

- renal structure proteins and sodium transport

- the 11-beta-hydroxysteroid dehydrogenase

- the Integrative regulation of sodium sodium