Witte: B Cell Development (Proc Taos New Mexico Jan/Feb 1988) (Hardcover)

Describes the molecular biology and regulation of B cell repertoire expression, B cell triggering and tolerance induction, and the role of defined interleukins in B cell development, differentiation, and isotope expression. Also covers "in vivo" development in neonates and adults and the role of defined "in vivo" systems for B cell development. Discusses B cell subpopulations, autoimmunity, and immunodeficient states, and gives details on the use of transgenic mice for analyzing B cell development and regulation.