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Books > Science & Mathematics > Biology, life sciences > Life sciences: general issues > Neurosciences

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Matrix Metalloproteinase Inhibitors - Specificity of Binding and Structure-Activity Relationships (Hardcover, 2012 ed.) Loot Price: R3,611
Discovery Miles 36 110
You Save: R795 (18%)
Matrix Metalloproteinase Inhibitors - Specificity of Binding and Structure-Activity Relationships (Hardcover, 2012 ed.): Satya...

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Matrix Metalloproteinase Inhibitors - Specificity of Binding and Structure-Activity Relationships (Hardcover, 2012 ed.)

Satya Prakash Gupta

Series: Experientia Supplementum, 103

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List price R4,406 Loot Price R3,611 Discovery Miles 36 110 | Repayment Terms: R336 pm x 12* You Save R795 (18%)

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Matrix metalloproteinases (MMPs) are proteolytic enzymes that are involved in many physiological and pathological processes. The field of MMP research is very important due to the implications of the distinct paralogs in both human physiology and pathology. Over-activation of these enzymes results in tissue degradation, producing a wide array of disease processes such as rheumatoid arthritis, osteoarthritis, tumor growth and metastasis, multiple sclerosis, congestive heart failure, and others. Thus MMP inhibitors are candidates for therapeutic agents to combat a number of diseases. The present book discusses the design and development of different classes of inhibitors of important classes of MMPs, such as gelatinases and collagenases. The articles focus specifically on structure-activity relationships of all classes of compounds and on their modes of action and specificity of binding with the receptors based on experimental and theoretical studies. These studies constitute a valuable asset for all those involved in drug development.

General

Imprint: Springer Basel
Country of origin: Switzerland
Series: Experientia Supplementum, 103
Release date: April 2012
First published: 2012
Editors: Satya Prakash Gupta
Dimensions: 235 x 155 x 18mm (L x W x T)
Format: Hardcover
Pages: 286
Edition: 2012 ed.
ISBN-13: 978-3-03-480363-2
Categories: Books > Medicine > Pre-clinical medicine: basic sciences
Books > Science & Mathematics > Biology, life sciences
Books > Medicine > Pre-clinical medicine: basic sciences > Physiology
Books > Science & Mathematics > Biology, life sciences > Life sciences: general issues
Books > Medicine > Pre-clinical medicine: basic sciences > Physiology > Cellular physiology
Books > Science & Mathematics > Biology, life sciences > Life sciences: general issues > Neurosciences
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LSN: 3-03-480363-X
Barcode: 9783034803632

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