Microarray analysis is a highly efficient tool for assessing the
expression of a large number of genes simultaneously, and offers a
new means to classify cancer and other diseases. Gene expression
profiling can also be used to predict clinical outcome and response
to specific therapeutic agents. This survey spans recent
applications of microarrays in clinical medicine, covering
malignant disease including acute leukaemias, lymphoid malignancies
and breast cancer, together with diabetes and heart disease.
Investigators in oncology, pharmacology and related clinical
sciences, as well as basic scientists, will value this review of a
promising new diagnostic and prognostic technology.
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