Learn why some drug discovery and development efforts succeed . . . and others fail
Written by international experts in drug discovery and development, this book sets forth carefully researched and analyzed case studies of both successful and failed drug discovery and development efforts, enabling medicinal chemists and pharmaceutical scientists to learn from actual examples. Each case study focuses on a particular drug and therapeutic target, guiding readers through the drug discovery and development process, including drug design rationale, structure-activity relationships, pharmacology, drug metabolism, biology, and clinical studies.
"Case Studies in Modern Drug Discovery and Development" begins with an introductory chapter that puts into perspective the underlying issues facing the pharmaceutical industry and provides insight into future research opportunities. Next, there are fourteen detailed case studies, examining:
All phases of drug discovery and development from initial idea to commercialization
Some of today's most important and life-saving medications
Drugs designed for different therapeutic areas such as cardiovascular disease, infection, inflammation, cancer, metabolic syndrome, and allergies
Examples of prodrugs and inhaled drugs
Reasons why certain drugs failed to advance to market despite major research investments
Each chapter ends with a list of references leading to the primary literature. There are also plenty of tables and illustrations to help readers fully understand key concepts, processes, and technologies.
Improving the success rate of the drug discovery and development process is paramount to the pharmaceutical industry. With this book as their guide, readers can learn from both successful and unsuccessful efforts in order to apply tested and proven science and technologies that increase the probability of success for new drug discovery and development projects.
Learn why some drug discovery and development efforts succeed . . . and others fail
Written by international experts in drug discovery and development, this book sets forth carefully researched and analyzed case studies of both successful and failed drug discovery and development efforts, enabling medicinal chemists and pharmaceutical scientists to learn from actual examples. Each case study focuses on a particular drug and therapeutic target, guiding readers through the drug discovery and development process, including drug design rationale, structure-activity relationships, pharmacology, drug metabolism, biology, and clinical studies.
"Case Studies in Modern Drug Discovery and Development" begins with an introductory chapter that puts into perspective the underlying issues facing the pharmaceutical industry and provides insight into future research opportunities. Next, there are fourteen detailed case studies, examining:
All phases of drug discovery and development from initial idea to commercialization
Some of today's most important and life-saving medications
Drugs designed for different therapeutic areas such as cardiovascular disease, infection, inflammation, cancer, metabolic syndrome, and allergies
Examples of prodrugs and inhaled drugs
Reasons why certain drugs failed to advance to market despite major research investments
Each chapter ends with a list of references leading to the primary literature. There are also plenty of tables and illustrations to help readers fully understand key concepts, processes, and technologies.
Improving the success rate of the drug discovery and development process is paramount to the pharmaceutical industry. With this book as their guide, readers can learn from both successful and unsuccessful efforts in order to apply tested and proven science and technologies that increase the probability of success for new drug discovery and development projects.
Imprint | John Wiley & Sons |
Country of origin | United States |
Release date | April 2012 |
Availability | We don't currently have any sources for this product. If you add this item to your wish list we will let you know when it becomes available. |
First published | 2012 |
Editors | Xianhai Huang, Robert G Aslanian |
Format | Electronic book text |
Pages | 480 |
Edition | 1st edition |
ISBN-13 | 978-1-118-21967-6 |
Barcode | 9781118219676 |
Categories | |
LSN | 1-118-21967-8 |